Lupus – Types, Symptoms, Risks, and Management

Lupus – Types, Symptoms, Risks, and Management

Lupus is a long-term autoimmune disease that makes the body’s immune system become hyperactive and attack healthy tissue. This complex condition is also called the “disease of a thousand faces”. Every year, around 16,000 new cases of the disease are reported, according to the Lupus Foundation of America. While there is no permanent cure for the disease yet, its treatment focuses on preventing flare-ups, easing symptoms, and reducing inflammation.

Types
Doctors usually categorize the condition into the following types:

  1. Systemic Lupus Erythematosus (SLE): This is the most common type, affecting multiple parts of the body, like the kidneys, skin, joints, heart, nervous system, and lungs. Symptoms of SLE may get worse during flares and improve during remission.
  2. Cutaneous lupus: This type is generally limited to the skin and can cause rashes and permanent lesions with scarring. It can be further categorized as:

    Acute cutaneous lupus: Here, one can observe a butterfly rash or a red rash appearing on the cheeks and bones.

    Subacute cutaneous lupus: This subtype causes the formation of a red, raised, scaly rash, generally in areas that have been exposed to sunlight. It typically does not lead to scarring.

    Chronic cutaneous lupus : Also known as discoid lupus, this subtype causes a red or purple rash and can lead to skin discoloration, scarring, and hair loss.

  3. Neonatal Lupus: This is an extremely rare form of the disease and develops in infants whose birth parents have certain autoimmune antibodies. These antibodies are transferred via the placenta. Symptoms may include a skin rash, low blood cell count, and liver problems after birth. It is important to note that mothers who have antibodies may or may not experience symptoms of lupus.

Common symptoms
The symptoms can vary depending on the part of the body affected. The inflammation can affect tissues and organs in various regions like the joints, skin, heart, blood, lungs, brain, and kidneys. These symptoms vary from individual to individual and may be permanent, appear or disappear suddenly, or cause occasional flares. According to the Centers for Disease Control and Prevention (CDC), the most common symptoms include

  1. High fever
  2. Fatigue
  3. Body aches
  4. Joint pain
  5. Rashes
  6. Skin lesions
  7. Shortness of breath
  8. Sjögren’s syndrome, which includes chronic dry eyes and dry mouth
  9. Pericarditis and pleuritis
  10. Headaches
  11. Confusion
  12. Memory loss

Inflammation from the condition can also lead to complications in the kidneys, lungs, and blood.

Lupus and photosensitivity
Many people with this autoimmune disease may also have photosensitivity. This makes them particularly sensitive to ultraviolet radiation, a type of radiation found in sunlight and certain types of artificial light. Exposure to UV rays can lead to photosensitive rashes with the presence of an antibody called SSA (Ro), fatigue, joint pain, and swelling. People with the condition who want to step out in the sun must wear sun-protective clothing and sunscreen.

Causes
While the causes of the condition are still unknown, the following factors may trigger its symptoms:

  1. Environment: Potential environmental triggers include stress and exposure to toxins such as silica dust.
  2. Genetics: More than 50 genes associated with the illness have been identified. People with a family history of this autoimmune disease are at an increased risk of developing it themselves.
  3. Hormones: Atypical hormone levels, such as increased levels of estrogen, could lead to lupus.
  4. Infections: There may be a link between this autoimmune disease and infections like cytomegalovirus and Epstein-Barr.
  5. Treatments: Long-term use of certain treatment options has been linked to this autoimmune disorder. These include specific prescriptions for conditions like rheumatoid arthritis, inflammatory bowel disease, and ankylosing spondylitis.

Risk factors
Certain groups are at a higher risk of developing the condition. These include

  1. Gender: Women are more likely to develop the condition than men, but it may be more severe in men.
  2. Age: While the illness can occur at any age, it most commonly develops in people between the ages of 15 and 44.
  3. Family history: People with a family history of this autoimmune condition are at a higher risk of developing the disease.
  4. Ethnicity: In the country, the condition is more common among people of color.

Treatment
Diagnosing lupus can be difficult due to the varied symptoms. Tests can include biomarkers that include proteins, antibodies, genetics, and other factors to indicate the body’s response to treatment, blood tests, urine tests, tissue biopsies, and imaging tests like X-rays.

Treatment for the condition aims to reduce inflammation, prevent flare-ups, and protect organs from damage. Depending on the severity and symptoms, each person’s treatment plan may look different. The most common treatments include prescriptions to treat rashes and arthritis symptoms caused by the condition. Additionally, certain prescriptions can target a specific part of the immune system to control inflammation. Further, biologics may be prescribed to treat symptoms of SLE. Doctors may also prescribe other therapies to treat complications like seizures and infections that may be brought on by lupus.

Natural management options
In addition to formal therapies, home remedies and lifestyle changes can help people manage the condition better.

  1. Make better food choices: Balanced meals with moderate amounts of fruits, vegetables, whole grains, and protein are a great way to manage health conditions. The symptoms may vary greatly from person to person, so it is important to speak to a doctor to find out the best-recommended nutrition plan. Lifestyle changes may include adding sources rich in omega-3 fatty acids, increasing intake of vitamins D and B, and avoiding foods with cholesterol, saturated fats, and sodium.
  2. Get moderate exercise: Low-impact exercises like walking, swimming, pilates, and yoga can help strengthen the body without aggravating the risk of joint inflammation. It can also help promote heart, lung, bone, and joint health and have a positive impact on one’s mental health.
  3. Build a community: Many people with autoimmune diseases could be concerned about social isolation. So, one may benefit from having an understanding support system, which could include friends, families, or online communities.
  4. Manage stress: As stress can trigger flare-ups, managing stress levels and adopting healthy lifestyle skills can help one manage the disease.
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Known Signs of Hemophilia and Anemia

Bleeding disorders refer to a group of conditions like hemophilia or anemia that interfere with normal blood functions in the body. Hemophilia affects the ability of the blood cells to clot naturally, while anemia lowers hemoglobin count in the red blood cells. These conditions exhibit a unique set of symptoms that can be identified. Early diagnosis helps doctors form a viable healthcare plan. So, it pays to know and identify the following symptoms. Hemophilia and Anemia: Understanding the difference Both conditions are common bleeding disorders. However, anemia & hemophilia signs are distinctly different from each other when it comes to the disease progression. The latter is a genetic disorder that affects the red blood cell’s ability to clot and close wounds. Certain clotting factors in the blood bind with the red blood cells to prevent uncontrolled bleeding. Anemia is a condition where the body lacks sufficient healthy red blood cells in the first place. Also, a low hemoglobin count affects the red blood cell’s ability to carry oxygen to vital organs and extremities via the circulatory system. Genetic mutation triggers most known types of hemophilia, while certain nutritional deficiencies in the body trigger common forms of anemia. Symptoms of hemophilia The absence of essential clotting factors in the blood can trigger a variety of noticeable and unusual symptoms. Uncontrolled bleeding Bleeding is one of the primary symptoms of hemophilia. It can happen under the skin or in the joints. As the red blood cells are unable to bind and clot, this pool of blood can trigger swelling, pain, and tightness in the joints. This symptom is most commonly noticeable in the knees, elbows, and ankles. Blood collecting under the skin can lead to buildups under the muscle and soft tissue to cause more painful bruising. This symptom is called hematoma in medical terminology. Frequent nosebleeds When the bleeding is triggered externally, it can result in frequent nosebleeds that can be difficult to stop. Note that external environmental factors and physical injuries generally cause nosebleeds. So, any unexplained bleeding could indicate a developing condition. Bleeding caused due to cuts, bruises, and vaccinations Lack of essential clotting factor VIII can trigger bleeding from the lightest of impacts, cuts, bruises, or even after losing a tooth. Some people experience sudden bleeding after taking a vaccination. This could be the body’s reaction to producing antibodies, but the strain could be too much to bear, resulting in bleeding from the extremities. Blood in urine or stool Excess blood in the urine or stool is a clear sign of disease progression. The urine and stools appear dark red or even blackish due to the presence of red blood cells mixed with the excreta. Immediate medical assistance is advisable for visual symptoms. Bleeding in infants Complicated pregnancies can be physically taxing for both the mother and the child leading to possible symptoms of hemophilia at birth. But in some rare cases, infants may experience internal bleeding in the head. Symptoms of anemia The most common types of anemia, including iron deficiency anemia and vitamin deficiency anemia, develop due to the lack of nutrients in the body. Therefore, anemia exhibits more physically taxing symptoms as the condition worsens. Tiredness Increased fatigue and weakness for no apparent reason is one of the main indicators of nutritional deficiencies. An unexplained decrease in overall stamina with no physical exertion or any activity during the day could mean low iron in the blood. Without iron, the body cannot produce enough red blood cells. And low hemoglobin means not enough oxygen is being circulated around vital organs in the body, thus resulting in fatigue induced by low energy levels. Respiratory symptoms Experiencing shortness of breath, chest pains, and even noticing an irregular heartbeat could indicate a possible anemic condition. An iron deficiency lowers hemoglobin count, and this means not enough oxygen is being circulated by the blood. Low hemoglobin affects the breathing rate as the body struggles to extract more oxygen resulting in shortness of breath. The heart must also put in extra efforts to pump the low hemoglobin blood forcefully, thus resulting in irregular heartbeats. Doctors refer to this condition as heart palpitations. These symptoms can also induce chest pains due to the sheer stress being put on the organ. Pale skin and damaged hair Skin and hair symptoms are visible indicators of a developing anemia condition. An iron deficiency results in low red blood cell production and indirectly affects the shade of the skin. Pale skin is noticeably visible around the face, gums, lower lips, lower eyelids, and even on the nails. This symptom is more visually obvious among people who flaunt a lighter skin tone. Also, hair thinning, hair fall, and a damaged scalp is a clear sign of iron deficiency. Treatment options Note that anemia & hemophilia signs never overlap. Once the primary indicators are confirmed, doctors quickly suggest blood tests to identify the leading causes or triggers. Knowing the differences can help with prompt diagnosis even though both the conditions are bleeding disorders. It is even possible to recover from common forms of anemia within 2 to 3 months. Hemophilia is a more serious bleeding disorder that is treated by introducing the missing clotting factors. Doctors also suggest prescriptions that help stimulate the body to release more clotting factors. However, a transfusion offers more promising results for moderate to severe progression. Effective preventive measures and home remedies can help lower the risk of bleeding. These conditions cannot be completely cured. But it is possible to improve the quality of life by incorporating healthy lifestyle habits. Prescriptions and treatments only help slow down the disease progression.

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Avoid These 8 Foods to Manage Lupus Flareups

Lupus is one of the commonly diagnosed autoimmune diseases wherein the immune system attacks the body and healthy cells of different organs. Inflammation, one of the leading symptoms of lupus, can affect the heart, lungs, brain, skin, kidneys, blood cells, and major joints as the condition progress. Lupus can be managed with early diagnosis and treatment. Eliminating certain foods can help manage and reverse the progression of this autoimmune disorder. Here are eight such foods to avoid. Salt Salt is one of the most popular condiments that gives flavor to all foods and even some beverages. However, the sodium found in salt is bad for someone already suffering from lupus symptoms. Excessive sodium intake increases the risk of high blood pressure and heart attack linked to lupus. It is better to control salt intake once the condition is diagnosed. Nutritionists recommend ordering sauces and appetizers without salt so that some can be added when necessary while serving the food. Salt should be consumed in moderation or substituted for some other condiment that adds flavor to the food. Popular alternatives include pepper, lemon, herbs, curry powder, and turmeric. Processed meats Precut meats, deli meats, and other types of red meats bought off the shelves in the supermarket are laced with additives and preservatives and are high in saturated fat content. These include sausages, bacon, hot dogs, pork, beef, and other fatty cuts of red meats should be eliminated from daily foods. The high-fat content can trigger an imbalance in cholesterol levels, thus increasing the risk of a heart attack. Also, red meats have minimal beneficial nutrients, so it is better to switch to fish options that are rich in omega-3 fatty acids. In place of meats, salmon, tuna, mackerel, sardines, and herring are excellent substitutes for healthy fats and proteins. Refined and baked goods Most processed foods, baked goods, and confectionaries in the supermarket are rich in fats, sugar, and salt. These include refined bread, pastas, rice, sweets, cakes, biscuits, breakfast cereals, syrups, and dressings. Processed and refined foods can trigger inflammation, one of the main triggers of lupus flareups. Also, the body’s digestive system can process only a finite number of calories and carbohydrates. Any excess left over in the bloodstream can elevate cholesterol levels. So, it is better to switch to wholesome alternatives in grains and baked goods. Whole foods are rich in soluble fibers that aid digestion and further prevent gut complications, thus boosting immunity. Alfalfa Lupus is an autoimmune condition, which means the flareups are triggered due to the body’s immune system attacking its own healthy cells. Alfalfa sprouts contain specific L-canavanine compounds that are known to either trigger or mimic lupus syndrome. These sprouts can stimulate the immune system and raise inflammatory responses. So, it is necessary to eliminate these sprouts if any underlying symptoms flare up. Alfalfa can also cause fatigue and muscle weakness and trigger sharp bouts of pain as the body rejects the compounds. Garlic Garlic is one of the most potent herbs belonging to the allium family of vegetables. Nutritionists recommend including garlic for its anti-inflammatory and potent chronic disease-fighting properties. However, garlic contains compounds like ajoene, thiosulfates, and allicin, all of that can trigger lupus flareups. Garlic is also an active stimulant that puts the immune system into hyperdrive, making it worse for someone who is already suffering from lupus symptoms. It is okay to consume garlic in moderation, but nutritionists recommend avoiding the herb while undergoing treatment for lupus. Nightshade vegetables Nightshade vegetables boast a rich source of antioxidants that help reverse and prevent oxidative damage to healthy cells. One of the key compounds in nightshade vegetables is anthocyanins. It lowers the risk of many cancers and chronic infections and also helps manage diabetes among adults to a great extent. Top picks include tomatoes, peppers, and eggplants used in daily food preparations. However, several of these vegetables may trigger inflammation and cause the symptoms to flareup upon regular intake. Though studies are not conclusive of this observation, nutritionists still suggest it is better to eliminate and substitute nightshade vegetables for cruciferous and leafy greens as an alternative source of antioxidants. Echinacea Nutritionists also suggest using certain supplements to support the immune system and boost protection against common colds and infections. Echinacea is extracted from a common coneflower plant and is quite a resourceful supplement given to manage blood sugar and prevent inflammation. It boasts a number of qualities and is quite the potent naturally occurring supplement that helps lower the risk of several chronic complications. However, it is also one of the number one triggers linked to lupus flare-ups and should be avoided after a diagnosis is confirmed. In fact, echinacea supplements are generally avoided for most commonly diagnosed autoimmune diseases. Flavored sodas and aerated drinks Flavored drinks and fizzy sodas contain the richest concentration of sugar in liquid form. Unknowingly or willingly, people are consuming several spoons of sugar with just a few glasses of these fizzy drinks. Sodas can severely impact blood sugar levels, and the resulting imbalance can trigger complications among those who are already diabetic. Studies also show that lupus tends to increase insulin resistance among older adults. Even natural fruit juices contain fructose, a natural sugar that can trigger an imbalance in blood sugar levels. It is advisable to consult with a nutritionist to discuss suitable alternatives to processed and store-bought beverages. Understand that changes in daily nutrition should only be done under the careful supervision of certified nutritionists. It is common for the human body to experience an adverse reaction when certain foods are substituted or eliminated from daily meal plans. It is advisable to discuss all the pros and cons before making any changes for the long term. Older adults must be extra vigilant and pay close attention to any discomforts that persist after making a change.

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