Multiple Myeloma Causes, Signs, and Treatments
Multiple myeloma is an uncommon and rare cancer, typically diagnosed in adults. With any form of cancer, the cells in the body mutate and grow out of control. In myeloma, cancer specifically affects plasma cells in the bloodstream. These cells are a vital immune system component found in the bone marrow. Myeloma develops slowly and destroys plasma functioning, thus compromising immunity. Here is everything one must know about myeloma and its progression. Major causes of multiple myeloma Genetics is one of the main trigger factors linked to conditions like multiple myeloma. Research suggests that a mutation in the plasma cells triggers the rapid and uncontrolled multiplication of cells in the area. Mutations are known to activate oncogenes or deactivate suppressor genes, resulting in cancer development. In addition to changes in the cell, missing chromosomes from the genetic code directly impact the progression of cancer. This includes missing chromosome 17 or the translocation of chromosomes where they switch characteristics. Any abnormalities in the bone marrow can also make the cancer progress faster and become more aggressive. Other known risk factors Advancing age Multiple myeloma affects a very small group of young people as it is mainly diagnosed among older adults above the age of 65.
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